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Many Researchers and Companies Will Aim to Produce Small Molecule Reprogramming Therapies
The typical path for any program in biomedical research and development is to first demonstrate interesting results in animal studies using forms of genetic engineering or gene therapy, and then find small molecules that adjust the same mechanism. Small molecules are never as good as genetic manipulations, the size of the effect is always smaller, usually much smaller, and there are inevitably side-effects. Small molecule development is much easier to conduct, however, more familiar to investors and regulators and program managers, a well-trodden path. Thus while the future of medicine is gene therapy, in search of large e...
Source: Fight Aging! - September 21, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

How Could Digital Technology Make An Impact On Primary Care?
I truly hope that very soon I do not have to make an appointment at the GP when I suspect signs of a disease, but my GP will send me a message that she spotted something irregular in my latest test results and my digital health data, so I’d better visit. Let me show you in detail how primary care should be carried out in the future! Digital health should become an organic part of primary care in the future I live a fairly healthy life. I use data to improve my lifestyle and to make better decisions by optimising my sleep pattern, my physical, my cognitive or my emotional abilities; and I had several genetic tests....
Source: The Medical Futurist - September 21, 2023 Category: Information Technology Authors: berci.mesko Tags: Digital Health Research Healthcare Innovation technology wearables GP primary care general practitioner Source Type: blogs

In Other Words: Sandboxes Aren ’t Just for Kids
Did you know that kids aren’t the only ones playing around in sandboxes? The term sandbox may evoke a childhood memory of sensory play, but it’s also used to describe a virtual environment where someone can learn from digital products. Credit: NIGMS. High quantities of data that can be hard to manage, store, and understand are increasingly driving biomedical research. Scientists need access to high-performance computer infrastructure along with bioinformatics tools to do cutting-edge research, but often these resources are out of reach for smaller institutions. Cloud computing can provide access to top-of-the...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 20, 2023 Category: Research Authors: Chrissa Chverchko Tags: Tools and Techniques Bioinformatics Computational Biology Cool Tools/Techniques In Other Words Source Type: blogs

The Unexpected Virtual Solution Elevating the Patient Experience
The following is a guest article by Holly Miller, President at Collette Health (formerly MedSitter) Amid the many challenges in healthcare, an emerging central theme is how to balance technological innovation with a compassionate human touch. Luckily, the advent of AI-enabled virtual care and machine learning has introduced a whole new world of virtual clinical observation. This not only bridges the gap between empathy and technology but goes beyond mere observation, offering a tech-assisted safety net that enhances the overall patient experience. The patient experience has always been a top concern, but health systems con...
Source: EMR and HIPAA - September 20, 2023 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning C-Suite Leadership Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring Collette Health Holly Miller MedSitter NLP Nurse Sitting Patient Communication Pa Source Type: blogs

Featured Health IT Job: Staff Nurse III – Information Technology at Natividad
We like to regularly feature a healthcare IT job that might be of interest to readers. Today, we’re featuring the Staff Nurse III – Information Technology at Natividad position that was recently posted on Healthcare IT Central. This position was posted by Natividad and is in Salinas, California. Here’s a description of the position: Inspiring Healthy Lives Through Community At Natividad, our dedication to the people of Monterey County is at the heart of everything we do—from the health care services we provide to the specialized programs we promote. This commitment to our community spans more than 130 ...
Source: EMR and HIPAA - September 20, 2023 Category: Information Technology Authors: Health IT Jobs Tags: Career and Jobs Healthcare IT Health IT Jobs Healthcare IT Jobs Information Technology Jobs Job Seekers Natividad Jobs Staff Nurse III Source Type: blogs

Aging Rate Indicators as Speedometers for Aging Research
Is it possible to measure the pace of aging at any given moment? Are there biomarkers that reveal not the biological age of the individual, but rather how fast that biological age is changing? The field is presently focused on developing measures of biological age, such as the extensive work on epigenetic clocks. Some information about pace of aging might be inferred from whether biological age is higher or lower than chronological age, assuming a biological age measurement that is actually accurate, something that still a topic for contention. But that doesn't say anything about the momentary pace of aging at any given ti...
Source: Fight Aging! - September 20, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A 50-something with Regular Wide Complex Tachycardia: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith.  Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

A 50-something with Regular Wide Complex Tachycardiaa: What to do if electrical cardioversion does not work?
Case submitted by anonymous. Written by Smith.  Ken ' s piece at the bottom is excellent.A 50-something presented with sudden onset palpitations 8 hrs prior while sitting at desk at work. He had concurrent sharp substernal chest pain that resolved, but palpitations continued.Over past 3 months, he has had similar intermittent episodes of sharp chest pain while running, but none at rest. Past medical history includes coronary stenting 17 years prior. A brief chart review revealed his most recent echo in 2018, with LV EF 67%, “very small” inferior wall motion abnormality.Initial ED ECG:What do you think?This wa...
Source: Dr. Smith's ECG Blog - September 20, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Healthcare IT Regulations – What Needs to Be Added and What Needs to Be Removed
There are a lot of rules and regulations in place in the world of healthcare. These are put into place in order to protect patients and organizations. However, the world of healthcare is constantly changing and evolving as we come up with new ideas and solutions. Have the regulations done the same though? Or are there areas that are missing regulations? Or are there areas in healthcare where past regulations are now too restrictive and are holding us back? In search of answers to these questions, we reached out to our incredibly beautiful Healthcare IT Today Community to see what areas they would add, remove, or update re...
Source: EMR and HIPAA - September 19, 2023 Category: Information Technology Authors: Grayson Miller Tags: Administration Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System LTPAC Regulations 1upHealth 4medica Amanda Heidemann Andrea Mazzoccoli Andrew Norden MD Bill Charnetski Cheryl Cheng Commur Source Type: blogs

Reasons, Rewards, and Tips for a More Accessible and Inclusive Web
The following is a guest article by Ben Cash, Founding Partner and CEO at Reason One The end of September marks International Week of the Deaf, followed soon after by Blind Americans Equality Day. Both are reminders of the need to make online resources accessible to all. Supporting this is the Americans with Disabilities Act (ADA), intended to protect the civil rights of persons with disabilities when it comes to areas like employment, government services, public accommodations, transportation, and telecommunications. For any organization – and particularly healthcare entities and systems – accessibility should...
Source: EMR and HIPAA - September 19, 2023 Category: Information Technology Authors: Guest Author Tags: C-Suite Leadership Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Accessibility Ada Automated Tools Ben Cash DE&I Digital Accessibility ESG Healthcare Accessibility Reason One Scre Source Type: blogs

Integral Secures $6.9 Million Seed Round Led by Haystack to Maximize Data Privacy and Quality
The General Partnership, Virtue Ventures, Caffeinated Capital, Array Ventures, GreatPoint Ventures, LiveRamp Ventures, Venrex, and Also Capital also Invest to Support the First Privacy Preserving Data Compliance Software Built for Pharma, Life Sciences, and Healthcare Enterprises Integral, an innovator in safeguarding privacy and maximizing data quality, today announced it raised a $6.9 million seed round to protect sensitive health data and provide automated expert certification software that enables health and life sciences companies access to compliant, rich, de-identified data in hours, rather than months. The seed rou...
Source: EMR and HIPAA - September 19, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Aashay Sanghvi Abhishek Chandra Airbyte Also Capital Amruta Moktali Andrew Arruda Array Ventures Caffeinated Capital Dr. Bradley Malin Flexpa GreatPoint Ventures Haystack Health IT Funding Heal Source Type: blogs

In Search of Immune System Differences in Long-Lived Mammals
What are the mechanisms that allow long-lived mammals to be long-lived? It remains to be seen as to whether it will be cost-effective and of sizable benefit to isolate specific genetic differences that can be used as a basis for therapies in humans, but it isn't a terrible idea to conduct the search. Clearly cancer suppression is an interesting topic, and one it might well be possible to build novel therapies based on the study of whales and elephants. Another good place to start is the operation of the immune system. The age-related decline of immune function is clearly important to the onset and progression of age-relate...
Source: Fight Aging! - September 19, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Chatting Apton Acquisition with PacBio CEO Christian Henry
PacBio CEO Christian Henry chatted with me recently by teleconference on a variety of topics, but the focus was the recent PacBio acquisition of Apton Biosystems for $85M in equity.   As a regular reminder, my employer’s CEO reports in a sense to Henry, as he’s on the Board of Directors.  A particularly interesting revelation by Henry is that PacBio had its eye on Apton in late 2021, essentially as soon as they completed theOmniome acquisition announced in July 2021 that formed the foundation for their now-released Onso short read instrument.     PacBio believed then that the desktop instrument design from Omniome...
Source: Omics! Omics! - September 19, 2023 Category: Bioinformatics Authors: Keith Robison Source Type: blogs

Ensuring Fairness in Medical Education Assessment
This study takes a first step in centering the margins as we as medical educators grow our understanding of the dynamics of promoting fairness in assessment. Future studies should explore feedback with intentional inclusion and involvement of diverse students, teachers, and researchers at every stage of the research process from conceptualization through dissemination and application of the new learning. We thank our participants for their time and candor discussing this sensitive topic and the Group on Educational Affairs for funding our work. Thank you for your time and attention and the focus that you’ll put on th...
Source: Academic Medicine Blog - September 18, 2023 Category: Universities & Medical Training Authors: amrounds Tags: AM Podcast AM Podcast Transcript Academic Medicine podcast assessment equity Macy Foundation medical education Source Type: blogs

Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs